<2>Depression May Start with an Energy Problem in Brain Cells
<3>Understanding the Energy Imbalance in Depression
Research has long suggested that depression is linked to changes in brain chemistry and function. However, a recent study has shed new light on the role of energy production in the development of depression. The study found that brain and blood cells in young adults with major depressive disorder produced more energy molecules at rest but struggled to increase energy production when needed.
WHO estimates that over 300 million people worldwide suffer from depression, making it one of the leading causes of disability globally. The symptoms of depression can vary widely, but common symptoms include fatigue, low motivation, and a lack of interest in activities that were once enjoyable.
The study’s findings suggest that the energy imbalance in brain cells may be a key contributor to these symptoms. When cells produce more energy molecules at rest, it can lead to a buildup of energy that is not being used. This can cause cells to become less responsive to signals that tell them to increase energy production when needed.